The clinical significance of anti-Müllerian hormone evaluation in gynecological endocrinology

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The clinical significance of anti-Müllerian hormone evaluation in gynecological endocrinology.

Anti-Müllerian hormone (AMH) is a homodimeric glycoprotein, a member of the transforming growth factor-β superfamily. Over the last decade, a large number of studies examining the multiple roles of AMH have been published. AMH levels accurately reflect the ovarian follicular reserve and could, therefore, be considered as an extremely sensitive marker of ovarian aging and a valuable tool in the ...

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Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare.

Anti-Müllerian hormone (AMH), a member of the transforming growth factor β superfamily of growth and differentiation factors, is expressed in granulosa cells of preantral and small antral ovarian follicles. In humans, AMH appeared to regulate recruitment and growth of small ovarian follicles. Furthermore, circulating AMH concentrations were elevated in women with granulosa-cell tumors (GCT). In...

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Anti Mullerian Hormone and its role in Gynecological Endocrinology: A Review

Anti Mullerian Hormone (AMH) is a glycoprotein belonging to the family of transforming growth factor-beta. The molecule has evolved in the last few decades for the assessment of ovarian reserve in females. Additionally this hormone has been found to be useful in predicting the success of in-vitro fertilization, marker of polycystic ovarian syndrome, granulosa cell tumor of ovary and prediction ...

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Anti - Müllerian hormone in sheep follicles ( 1 )

The purpose of this work was to study anti-MOllerian hormone (AMH) secretion during ovarian development in sheep before and after birth. We used avidinbiotin immunocytochemistry and a monoclonal antibody specific for ruminant AMH. Only granulosa cells have an immunoreactivity ; this immunoreactivity was influenced by animal age and by the degree of follicular development. In the fetus, no immun...

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Anti-Müllerian hormone: clairvoyance or crystal clear?

The clinical use of anti-Müllerian hormone (AMH) has increased exponentially due to its unique relationship with the ovarian reserve and ability to predict ovarian response, facilitate pretreatment counselling and individualize treatment strategies to minimize the risk of ovarian hyperstimulation syndrome. There is now a rapidly increasing literature examining additional possibilities for AMH, ...

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ژورنال

عنوان ژورنال: HORMONES

سال: 2011

ISSN: 1109-3099

DOI: 10.14310/horm.2002.1299